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| S | Sona, Oliver | Varnod, the widow |
| Sabin, Charles | Sons of Liberty | Villepontoux, ________ |
| Sage, Ann | Sothel, Gov. Seth | Villepontoux Branch |
| St. Augustine, Florida | South Carolina Railway | Villepontoux, Zachariah |
| St. George's Church, Dorchester | Southeastern Water Corp. | Von Aarsens, Franciscus |
| St. James Academy | Southern Railway | Vose, Capt. Carston William |
| St. James Episcopal Church Goose Creek | Spain, threat of invasion by | W |
| St. James Parish, Goose Creek | Spring Grove | Wade Family |
| St. John, Dr. Stephen | Stamp Act | Wagner, Capt. |
| St. Julien, Elizabeth de | Stanyarne, James | Walker, Clancy |
| St. Julien, Peter | State Road | Walker, Richard |
| St. Luke's Eposcopal Church Charleston | Steepbrook Plantation | Wallace, Rev. C. |
| St. Michael's Episcopal Church Charleston | Stepehnson | Walling, Don |
| St. Paul's Cathedral, London | Stevens, Lamb, a free negro | Walpole, Horace |
| St. Paul's Episcopal Church, Stono | Stevens, Mrs. Mary S. | Walter, Elizabeth |
| St. Paul's Episcopal Church, Summerville | Stevens, Norman | Walter, Thomas |
| St. Stephen's Episcopal Church Charleston | Stevens, Robert | Walter, William |
| Salley, Alexander S. Jr. | Stevens, Rev. Robert | Wando Indians |
| Salley, Elizabeth | Stevens Plantation | Wando River |
| Salter, Mrs. | Stevenson, Capt. James | Wapensaw, an Indian term |
| Samson, a runaway slave | Stewart, John | Waring, Benjamin |
| Sanders, John | Stitt, Elizabeth | Waring, Maj. Benjamin |
| Sanders, Capt. John | Stitt, William | Waring, Dr. Joseph, Ioor |
| Sanders, William | Stock, Law of | Waring, Samuel Gaillard |
| Sanders, Wilson | Stone Fleet | Waring, Thomas R. |
| Santee Canal | Stone, John | Warner, Samuel |
| Santee Canal Company | Stone Landing, SC | Warnock, Capt. S. C. |
| Santee Indians | Stone, Rev. Robert | Washing,, President George |
| Santee Settlement | Stoney, Arthur Jervey | Wassamassaw Baptist Church |
| Sanute, Indian chief | Stoney, Dwight | Wassamassaw Cavalry |
| Sarraw Indians | Stoney, Isaac Dwight | Wassamassaw Causeway |
| Saso, Frank Sr. | Stoney, Lt. Isaac Dwight | Wassamassaw Chapel of Ease, St. James Church |
| Saunders, Capt. James | Stoney, Louisa Cheves | Wassamassaw Mounted Club |
| Saunders, John | Stoney, P.G. | Wassamassaw Road |
| Sayle, Gov. | Stoney, Peter Gailliard | Wassamassaw School |
| Scarborough, Mrs. | Stoney, S. Procher | Wassamassaw, SC |
| Schnecking(h), Benjamin | Stoney, Samuel G. | Wassamassaw Swamp |
| Scotland | Stoney, Samuel Gaillard | Wateree Indians |
| Scott, William | Stoney, T. S. | Waterland, William |
| Secession | Stoney, Thomas Procher | Watkins, Mrs. Hilma |
| Secession Convention | Stoney, Capt. William Edmund | Watson, Dr. John |
| Secession, Ordinance of | Strawberry Democratic Club | Watson, Livinia |
| Second S.C. Regiment C.S.A. | Strawberry Ferry | Webb, Edward |
| Sedgefield | Strawberry Landing | Webster, Daniel |
| Seed, Polly | Strawberry Plantation | Webster, David |
| Seigniories, Established | Strawberry Station | Webster, Lt. Col. |
| Senkler, Elizabeth | Streator, James | Weekly, Edward |
| Senkler, William | Streator's Plantation | West, Gov. Joseph |
| Sequestered Estates | Strohecker, J. L. | West Virginia Development Co |
| Sewee Indians | Sugar, planted on Barbados | Westfield, Capt. |
| Shadow, A Race Horse | Sugar, imported | Westo Indian War |
| Shay's Rebellion | Sugar Act. | Westo Indians |
| Shepard, _________ | Sullivan's Island, SC | Weston, William |
| Sherman, Gen | Sully, Elizabeth | Whaley, William |
| Shingler, John N. | Summerville, SC | Whatley, C.W. |
| Shingler, S. | Sumter, Gen. | White House Plantation |
| Shingleton, Richard | Swint, Dr. John Hendrick | White, William |
| Shipley, William | T | Whitesville, SC |
| Shiver, Lagette | Tamplet, Peter | Whitney, Eli |
| Shringler, G. W. | Tares' Estate | Wiggins, Dr. J. B. |
| Shuler, John | Targate, SC | Wiggins, Dr. T. |
| Silk Hope Plantation | Target, SC | Wiggins, T. W. |
| Simms, William Gilmore | Tarhill, SC | Wigton Plantation |
| Sims, Rev. A. G. | Tarrif of 1828 | William, King of England |
| Sineath, Lloyd (E) | Tarkiln, SC | Williams, Capt. |
| Singleberry, Richard | Tarleton, Lt. Col. Banastre | Williams, Jane |
| Singleton, Benjamin | Tartar, a racehorse | Williams, Dr. John |
| Singleton, Capt. Benjamin | Taylor, Amerentia | Williams, Rev. Stephen |
| Singleton, Col. Benjamin | Taylor, Rev. J. W. | Williams, W. |
| Singleton, Col. | Taylor, Joseph | Williams, West |
| Singleton Family (negro) | Taylor, Peter | Williams, Rev. West |
| Singleton, James | Taylor, Capt. Peter | Williams, William |
| Singleton, Rebecca | Taylor, Lt. Peter | Williamson,, Rev Atkin |
| Singleton, Richard | Taylor, Mr. | Willoughby, Mrs. |
| Singleton, Richard | Ten Mile House Tavern | Wilson, Dr. J. |
| Singleton, Lt. Richard | Tennent, Dr. Charles | Wilson, John |
| Singleton, Thomas | Tennent, Mrs. | Wilson, Marion |
| Siouen Language | 30th Infantry Division, WWI | Wilson, Moses |
| Siri, Andrew | Thomas, Col. John P. | Wilson, Rev. Robert |
| Six Mile House | Thomas, Rev. Samuel | Wilson's Estate |
| Skene, Alexander | Thomas, W. B. | Windsor Hill Plantation |
| Smith, Amarinthia | Thomasen, Anne | Winlock, James |
| Smith, Benjamin | Thomason Blvd. | Winter, Capt. Hugh Strain |
| Smith, Capt. Benjamin | Thomason, Orven | Winter, T.H. |
| Smith, Maj. Benjamin | Thomason's Store | Winyah Indian War |
| Smith, Bishop | Thomson, Rev. John | Withers, William |
| Smith, Elizabeth Ann | Thorin, Capt. George M. | Withers, Mrs. Francis |
| Smith, G. | Thornley, Maj. Robert | Withers, James |
| Smith, G. C. | Thoroughgood Plantation | Withers, John |
| Smith, G. H. | Tobacco | Withers, John Sr. |
| Smith, Goerge | Tookerman, Richard | Withers, Richard |
| Smith, Dr. George | Tories: see Loyalists | Withers, Capt. Richard |
| Smith, George C. | Townsend, Mrs. Hepzibah | Withers, W. |
| Smith, George Henry | Townshend Act | Wolf's Castle Plantation |
| Smith, Henry | The Treasure of Pierre Gaillard, a novel | Wood, Ben |
| Smith, Mrs. Henry | Trinity College, Dublin | Wood, Robert |
| Smith, Henry A. M. | Trouillort, Philip | Wood, William |
| Smith, Henry Middleton | Turkish Spy, a novel | Woode, M. E. |
| Smith, J. | Turner, Fredrick Jackson | Woodlawn Heights Subdivision |
| Smith, James | Turner, Hattie | Woods, E. Calvin |
| Smith, Lt. James | Turner, Hattie V. | Woods, Vivian A. |
| Smith, Jane | Turner, L. C. | Woodstock Plantation |
| Smith, John | Turner, Weyman | Woorams, John |
| Smith, Mary | Tuscarora Indians | Worley, Richard a pirate |
| Smith, Mrs. | Tustian, Rev. | Wragg, Henrietta |
| Smith, Peter | Twenty-three Mile House | Wren, W. R. |
| Smith, Rebecca | Tyner, R. Harold | Wright, E. G. |
| Smith, Mrs. Sabina | U | Wright, John |
| Smith, T. H. | Union & States Rights Party | Wright Capt. John |
| Smith, T. Henry | Union College, Schenectady, NY | Wright, T. |
| Smith, Thomas | Union Party | Wright, Thomas |
| Smith, Col. Thomas | V | Y |
| Smith, (Gov.) Landgrave Thomas | Van Arrsens, Jan | Yeaman's Creek |
| Smith, Thomas Jr. | Vance, Maj. William | Yeamans Hall Plantation |
| Smith, Thomas Sr. | Vanderdussen, Col. Alexander | Yeamans, Sir John |
| Smith, Thomas Henry | Vanderdussen, Mrs. | Yeamans, Lady Margaret |
| Smith, William | Vanderdussen's Estate | Yemassee Indian War |
| Smithfield tract | Van Kleek, Loring E. | Yemassee Indians |
| Snow, Jacob | Varner, Dr. I. B. | "Yeowee", an Indian Term |
| Snow, James | Varner, J. | Yeshoe Plantation |
| Snow, Nathaniel | Varner School | Yon, Oliver |
| Snow, Dr. Nathaniel | Stoney, Pierre Gaillard |
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