Anyone researching the folks named in this land transaction?

Book I-3, p. 1	
7 & 8 Oct. 1767

SAMUEL CARNE, formerly a physician in Charleston, SC, now a merchant in
London, by his attorneys, JOHN ROSE, gentleman, & DR ROBERT WILSON, of
Charleston; to ALEXANDER PETRIE, gentleman, of Charleston, for L14,000
SC money, 2 adjoining lots #229 & #178 in Charleston, fronting on Broad
& Tradd Streets.  Whereas by L & R dated 1 & 2 Dec. 1758 ALEXANDER
CHISHOLME, vintner, of Charleston, sold SAMUEL CARNE lot #229 bounding
according to plat annexed to said release, which lot had been granted by
the Lords Proprs. to JOHN ELLIOTT; also half of lot #178, with its
edifices, etc., fronting N 50 ft. on Broad Street; 200 ft. deep;
bounding S on lot #229; W on MARY ELLIS (formerly EDWARD CROFT); E o
WILLIAM MATTHEWES (now SAMUEL CARNE); & whereas by L & R dated 18 & 19
Sept. 1763, ANTHONY MATTHEWES, gentleman, of Johns Island, St. Johns
Parish, Colleton Co., sold SAMUEL CARNE  the E half of lot #178, with
its edifies, bounding N 50 ft. on Broad Street; S & W on SAMUEL CARNE; E
200 ft. on JOHN DRAYTON; & whereas CARNE has been in possession of said
premises, commonly called Orange Garden, for several years past &
desires to sell the property on 4 June last appointed ROSE & WILSON his
attorneys; now they sell a part to PETRIE.  Witnesses:  JAMES LAURENS,
CHARLES PINCKNEY.  Before FENWICKE BULL, JP & P. Register.  REcorded 23
Nov. 1767.  Plat shows lot 229 bounding W on Mr. WATSONE; E on FREDERICK
GRIMKE, (formerly Lee); STEVENSON'S land, MR. MILLER; & PETER TIMOTHY.